Kosuke Ebina Selected Research

glucose utilization inhibitor (IGU)

7/2021	Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro.
7/2019	The add-on effectiveness and safety of iguratimod in patients with rheumatoid arthritis who showed an inadequate response to tocilizumab.

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Kosuke Ebina Research Topics

Disease

43	Rheumatoid Arthritis 11/2022 - 04/2009
13	Osteoporosis 11/2022 - 09/2013
9	Congenital Abnormalities (Deformity) 01/2022 - 11/2017
5	Hallux Valgus 10/2021 - 05/2018
5	Postmenopausal Osteoporosis 10/2021 - 09/2017
3	Inflammation (Inflammations) 11/2022 - 01/2009
3	Pain (Aches) 01/2022 - 01/2020
3	Arthritis (Polyarthritis) 01/2022 - 01/2009
3	Bone Resorption 07/2021 - 12/2016
1	Rheumatic Diseases (Rheumatism) 07/2022
1	Infections 02/2022
1	Low Back Pain (Lumbago) 12/2020
1	Osteoporotic Fractures 09/2020
1	Osteoarthritis 01/2020
1	Wounds and Injuries (Trauma) 01/2020
1	Ankylosis 09/2018
1	Crush Injuries 05/2018
1	Hyperlipidemias (Hyperlipidemia) 01/2018
1	Atherosclerosis 09/2015
1	Body Weight (Weight, Body) 03/2013
1	Gastroesophageal Reflux (GERD) 03/2013
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2013
1	Synovitis 12/2012
1	Hypoxia (Hypoxemia) 12/2011

Drug/Important Bio-Agent (IBA)

12	Pharmaceutical PreparationsIBA 02/2022 - 12/2012
10	Antirheumatic Agents (DMARD)IBA 02/2022 - 12/2012
8	Biological ProductsIBA 07/2021 - 01/2018
6	Denosumab FDA Link 07/2022 - 01/2017
5	Teriparatide (Parathar)FDA Link 03/2021 - 12/2016
4	GlucocorticoidsIBA 11/2022 - 10/2020
4	Janus Kinase InhibitorsIBA 02/2022 - 01/2020
4	Diphosphonates (Bisphosphonates)IBA 03/2021 - 01/2017
4	tocilizumab (atlizumab)FDA Link 09/2020 - 12/2012
3	Monoclonal AntibodiesIBA 07/2022 - 09/2020
3	Tumor Necrosis Factor InhibitorsIBA 01/2022 - 01/2021
3	romosozumabIBA 10/2021 - 11/2020
2	Prednisolone (Predate)FDA LinkGeneric 11/2022 - 03/2013
2	Methotrexate (Mexate)FDA LinkGeneric 02/2022 - 07/2019
2	tofacitinibIBA 07/2021 - 01/2020
2	Abatacept (Orencia)FDA Link 07/2021 - 09/2020
2	glucose utilization inhibitor (IGU)IBA 07/2021 - 07/2019
2	1- hydroxy- 5,8- bis(2- ((2- hydroxyethyl)amino)ethylamino)- 9,10- anthracenedioneIBA 01/2021 - 03/2013
2	Capsules (Microcapsules)IBA 01/2020 - 05/2018
2	Oxygen (Dioxygen)IBA 05/2018 - 12/2011
2	Vitamin K 2 (Vitamin K2)IBA 05/2016 - 09/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2015 - 12/2012
2	Interleukin-6 (Interleukin 6)IBA 07/2014 - 12/2012
2	Messenger RNA (mRNA)IBA 12/2011 - 01/2009
2	AdiponectinIBA 04/2009 - 01/2009
1	Indicators and Reagents (Reagents)IBA 11/2022
1	Serum AlbuminIBA 11/2022
1	C-Reactive ProteinIBA 11/2022
1	Immunoglobulin FragmentsIBA 01/2022
1	sarilumabIBA 07/2021
1	baricitinibIBA 07/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 07/2021
1	NF-kappa B (NF-kB)IBA 07/2021
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/2021
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 07/2021
1	Interleukin-6 InhibitorsIBA 01/2021
1	LigandsIBA 10/2020
1	cyclic citrullinated peptideIBA 02/2020
1	Thiostrepton (Gargon)IBA 12/2019
1	iguratimodIBA 07/2019
1	Apolipoproteins E (ApoE)IBA 01/2018
1	Apolipoprotein E3IBA 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Durapatite (Hydroxylapatite)IBA 01/2018
1	Apolipoprotein E4IBA 01/2018
1	alfacalcidolIBA 09/2017
1	Vitamin D FDA LinkGeneric 09/2017
1	Cholecalciferol (Vitamin D3)FDA Link 09/2017
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2017
1	Parathyroid Hormone (Parathormone)IBA 12/2016
1	YM 529IBA 05/2016
1	eldecalcitol (ED 71)IBA 05/2016
1	Tyrosine (L-Tyrosine)FDA Link 09/2015
1	Phosphotransferases (Kinase)IBA 09/2015
1	AutoantibodiesIBA 03/2014
1	Immunoglobulin G (IgG)IBA 03/2014
1	OsteocalcinIBA 09/2013
1	Etanercept (Enbrel)FDA Link 12/2012
1	Infliximab (Remicade)FDA Link 12/2012
1	Free RadicalsIBA 12/2012
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2012
1	Proteins (Proteins, Gene)FDA Link 12/2011
1	Therapeutic UsesIBA 01/2009
1	AntibodiesIBA 01/2009
1	CytokinesIBA 01/2009

Therapy/Procedure

9	Osteotomy 01/2022 - 11/2017
7	Therapeutics 03/2021 - 12/2012
7	Arthroplasty 11/2020 - 01/2017
2	Operative Surgical Procedures 01/2022 - 10/2021
2	Arthrodesis 12/2018 - 05/2018
2	Replacement Arthroplasty 09/2017 - 01/2017
1	Aftercare (After-Treatment) 01/2022
1	Reoperation 10/2021
1	Activities of Daily Living (ADL) 01/2021
1	Sutures (Suture) 01/2020
1	Drug Therapy (Chemotherapy) 11/2017